UniProt P0AFG0
Transcription termination/antitermination protein NusG (P0AFG0)
Transcription termination/antitermination protein NusG (UniProt P0AFG0): 20 experimental structures and 1 predicted model on GenesisL1, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0AFG0
- Protein
- Transcription termination/antitermination protein NusG
- Experimental structures
- 20
- Predicted models
- 1
- Pockets
- 10 · 7 records with a druggable one
Structures
21 records of P0AFG0 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2JVV | Solution Structure of E. coli NusG carboxyterminal domain | solution nmr | A | — | — |
| 2JVV | Solution structure of E. COLI nusg carboxyterminal domain | solution nmr | A | — | — |
| 2K06 | Solution structure of the aminoterminal domain of E. coli NusG | solution nmr | A | — | — |
| 2K06 | Solution structure of the aminoterminal domain of E. COLI nusg | solution nmr | A | — | — |
| 2KVQ | Solution structure of NusE:NusG-CTD complex | solution nmr | G | — | — |
| 2KVQ | Solution structure of NUSE:NUSG-ctd complex | solution nmr | G | — | — |
| 5MS0 | pseudo-atomic model of the RNA polymerase lambda-based antitermination complex solved by cryo-EM | electron microscopy | F | — | — |
| 5MS0 | Pseudo-atomic model of the RNA polymerase lambda-based antitermination complex solved by cryo-EM | electron microscopy | F | — | — |
| 6XAV | CryoEM Structure of E. coli Rho-dependent Transcription Pre-termination Complex bound with NusG | electron microscopy | L | — | 2 (best 0.78) |
| 6XAV | Cryoem structure of E. COLI rho-dependent transcription pre- termination complex bound with nusg | electron microscopy | L | — | — |
| 6XE0 | Cryo-EM structure of NusG-CTD bound to 70S ribosome (30S: NusG-CTD fragment) | electron microscopy | V | — | 1 (best 0.86) |
| 6XE0 | Cryo-EM structure of nusg-ctd bound to 70S ribosome (30S: nusg-ctd fragment) | electron microscopy | V | — | — |
| 7PY0 | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusG (NusG-EC in… | electron microscopy | G | — | 2 (best 0.78) |
| 7PY1 | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusG (the consensus NusG-EC) | electron microscopy | G | — | 2 (best 0.78) |
| 7PY6 | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA and NusG… | electron microscopy | G | — | — |
| 7PY7 | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA and NusG… | electron microscopy | G | — | 1 (best 0.80) |
| 7PY8 | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusG (NusG-EC in… | electron microscopy | G | — | — |
| 9GUR | 30S mRNA delivery complex TEC resolved (TEC only) | electron microscopy | Z | — | 1 (best 0.77) |
| 9GUW | 30S-TEC (TEC in expressome position) Inactive state 2 | electron microscopy | Z | — | — |
| 9GUX | 30S-TEC (TEC in expressome position) Inactive state 1 | electron microscopy | Z | — | 1 (best 0.77) |
| P0AFG0 | AlphaFold monomer V2.0 prediction for transcription TERMINATION/ANTITERMINATION protein nusg… | predicted | A | — | — |
Experiment against prediction
- 2JVV chain A against the predicted model P0AFG0: TM-score 0.88, RMSD 1.39 Å
- 2JVV chain A against the predicted model P0AFG0: TM-score 0.88, RMSD 1.39 Å
- 2KVQ chain G against the predicted model P0AFG0: TM-score 0.88, RMSD 1.39 Å
- 2KVQ chain G against the predicted model P0AFG0: TM-score 0.88, RMSD 1.39 Å
- 9GUR chain Z against the predicted model P0AFG0: TM-score 0.84, RMSD 1.84 Å
- 2K06 chain A against the predicted model P0AFG0: TM-score 0.82, RMSD 2.23 Å
- 2K06 chain A against the predicted model P0AFG0: TM-score 0.82, RMSD 2.23 Å
- 6XAV chain L against the predicted model P0AFG0: TM-score 0.78, RMSD 2.30 Å
- 6XAV chain L against the predicted model P0AFG0: TM-score 0.78, RMSD 2.30 Å
- 7PY6 chain G against the predicted model P0AFG0: TM-score 0.76, RMSD 2.55 Å
Elsewhere
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