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Solution structure of ci-mpr domain 5 bound to N-acetylglucosaminyl 6- phosphomethylmannoside

Analyse Solution structure of ci-mpr domain 5 bound to N-acetylglucosaminyl 6… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2KVB
Type: protein
Length: 148 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cation-independent mannose-6-phosphate receptor
UniProt: P08169
Pockets: 1 · best druggability 0.40

Structure

solution nmr · 1 distinct chain · 2% helix, 46% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cation-independent mannose-6-phosphate receptor	protein	148	2% helix, 46% strand	P08169

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	118	0.40	0.75	16	empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

2KVB · Solution structure of CI-MPR domain 5 bound to N-acetylglucosaminyl… · the same entry in another collection · chain A against A, TM-score 1.00
P08169 · AlphaFold monomer V2.0 prediction for cation-independent mannose-6-phosphate receptor… · a predicted model of the same protein · chain A against A, TM-score 0.86

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08169
Elsewhere: RCSB PDB 2KVB · PDBe 2KVB · UniProt P08169

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