UniProt P08169
Cation-independent mannose-6-phosphate receptor (P08169)
Cation-independent mannose-6-phosphate receptor (UniProt P08169): 13 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 40 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P08169
- Protein
- Cation-independent mannose-6-phosphate receptor
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 40 · 2 records with a druggable one
Structures
14 records of P08169 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1Q25 | Crystal structure of N-terminal 3 domains of CI-MPR | x-ray diffraction | A | — | — |
| 1Q25 | Crystal structure of N-terminal 3 domains of ci-mpr | x-ray diffraction | A | — | — |
| 1SYO | N-terminal 3 domains of CI-MPR bound to mannose 6-phosphate | x-ray diffraction | A, B | — | — |
| 1SYO | N-terminal 3 domains of ci-mpr bound to mannose 6-phosphate | x-ray diffraction | A, B | — | — |
| 1SZ0 | N-terminal 3 domains of CI-MPR bound to mannose 6-phosphate | x-ray diffraction | A, B | — | — |
| 1SZ0 | N-terminal 3 domains of ci-mpr bound to mannose 6-phosphate | x-ray diffraction | A, B | — | — |
| 2KVA | SOLUTION STRUCTURE OF CI-MPR ligand-free domain 5 | solution nmr | A | — | — |
| 2KVA | Solution structure of ci-mpr ligand-free domain 5 | solution nmr | A | — | — |
| 2KVB | Solution structure of CI-MPR domain 5 bound to N-acetylglucosaminyl 6-phosphomethylmannoside | solution nmr | A | — | — |
| 2KVB | Solution structure of ci-mpr domain 5 bound to N-acetylglucosaminyl 6- phosphomethylmannoside | solution nmr | A | — | — |
| 6UM1 | Structure of M-6-P/IGFII Receptor at pH 4.5 | electron microscopy | A | NAG | 20 (best 0.79) |
| 6UM1 | Structure of M-6-P/IGFII receptor at pH 4.5 | electron microscopy | A | NAG | — |
| 6UM2 | Structure of M-6-P/IGFII receptor and igfii complex | electron microscopy | A | NAG | — |
| P08169 | AlphaFold monomer V2.0 prediction for cation-independent mannose-6-phosphate receptor (P08169) | predicted | A | — | 20 (best 0.80) |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 3 records
Experiment against prediction
- 1SZ0 chain A against the predicted model P08169: TM-score 0.98, RMSD 1.20 Å
- 1SZ0 chain A against the predicted model P08169: TM-score 0.98, RMSD 1.20 Å
- 1SYO chain A against the predicted model P08169: TM-score 0.98, RMSD 1.24 Å
- 1SYO chain A against the predicted model P08169: TM-score 0.98, RMSD 1.24 Å
- 1SYO chain B against the predicted model P08169: TM-score 0.97, RMSD 1.24 Å
- 1SYO chain B against the predicted model P08169: TM-score 0.97, RMSD 1.24 Å
- 1SZ0 chain B against the predicted model P08169: TM-score 0.97, RMSD 1.28 Å
- 1SZ0 chain B against the predicted model P08169: TM-score 0.97, RMSD 1.28 Å
- 1Q25 chain A against the predicted model P08169: TM-score 0.96, RMSD 1.49 Å
- 1Q25 chain A against the predicted model P08169: TM-score 0.96, RMSD 1.49 Å
Elsewhere
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