Research workbench
Structures of adenylosuccinate synthetase from triticum aestivum and arabidopsis thaliana
Analyse Structures of adenylosuccinate synthetase from triticum aestivum and… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1DJ2
- Type
- protein
- Length
- 858 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Adenylosuccinate synthetase
- EC
- 6.3.4.4
- UniProt
- Q96529
- Ligands
- GDP
- Pockets
- 10 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Adenylosuccinate synthetase (EC 6.3.4.4) | protein | 429 | 36% helix, 21% strand | Q96529 |
Ligands and binding sites
- GDP · Guanosine-5'-diphosphate · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
10 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 149 | 0.83 | 0.99 | 22 | empty |
| 2 | 167 | 0.81 | 0.97 | 28 | empty |
| 3 | 642 | 0.77 | 0.83 | 64 | GDP |
| 4 | 677 | 0.76 | 0.82 | 61 | GDP |
| 5 | 436 | 0.71 | 0.82 | 51 | empty |
Interfaces
1 interface between chains.
- A–B · 2779 Ų buried · 39 hydrogen bonds · protein-protein
Compared structures
- 1DJ2 · Structures of adenylosuccinate synthetase from triticum aestivum and arabidopsis thaliana · the same entry in another collection · chain A against A, TM-score 1.00
- Q96529 · AlphaFold monomer V2.0 prediction for adenylosuccinate synthetase, chloroplastic (Q96529) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96529
- Elsewhere: RCSB PDB 1DJ2 · PDBe 1DJ2 · UniProt Q96529
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.