Research workbench
Structure of the E1064A mutant of the N-domain of wilson disease associated protein
Analyse Structure of the E1064A mutant of the N-domain of wilson disease associated… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2KOY
- Type
- protein
- Length
- 141 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Copper-transporting ATPase 2
- EC
- 3.6.3.4
- UniProt
- P35670
- Pockets
- 3 · best druggability 0.50
Structure
solution nmr · 1 distinct chain · 35% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Copper-transporting ATPase 2 (EC 3.6.3.4) | protein | 141 | 35% helix, 28% strand | P35670 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 242 | 0.50 | 0.74 | 33 | empty |
| 2 | 82 | 0.45 | 0.80 | 19 | empty |
| 3 | 100 | 0.39 | 0.76 | 19 | empty |
Compared structures
- 2KOY · Structure of the E1064A mutant of the N-domain of Wilson Disease Associated Protein · the same entry in another collection · chain A against A, TM-score 1.00
- P35670 · AlphaFold monomer V2.0 prediction for copper-transporting ATPase 2 (P35670) · a predicted model of the same protein · chain A against A, TM-score 0.57
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35670
- Elsewhere: RCSB PDB 2KOY · PDBe 2KOY · UniProt P35670
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