UniProt P35670
Copper-transporting ATPase 2 (P35670)
Copper-transporting ATPase 2 (UniProt P35670), EC 7.2.2.8: 13 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P35670
- Protein
- Copper-transporting ATPase 2
- EC
- 7.2.2.8
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 12 · 1 record with a druggable one
Structures
14 records of P35670 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2ARF | Solution structure of the Wilson ATPase N-domain in the presence of ATP | solution nmr | A | — | — |
| 2ARF | Solution structure of the wilson ATPase N-domain in the presence of ATP | solution nmr | A | — | — |
| 2EW9 | Solution structure of apoWLN5-6 | solution nmr | A | — | — |
| 2EW9 | Solution structure of APOWLN5-6 | solution nmr | A | — | — |
| 2KOY | Structure of the E1064A mutant of the N-domain of Wilson Disease Associated Protein | solution nmr | A | — | — |
| 2KOY | Structure of the E1064A mutant of the N-domain of wilson disease associated protein | solution nmr | A | — | — |
| 2LQB | Metal binding repeat 2 of the Wilson disease protein (ATP7B) | solution nmr | A | — | — |
| 2LQB | Metal binding repeat 2 of the wilson disease protein (ATP7B) | solution nmr | A | — | — |
| 2N7Y | NMR structure of metal-binding domain 1 of ATP7B | solution nmr | A | — | — |
| 2N7Y | NMR structure of metal-binding domain 1 of ATP7B | solution nmr | A | — | — |
| 2ROP | Solution structure of domains 3 and 4 of human ATP7B | solution nmr | A | — | — |
| 2ROP | Solution structure of domains 3 and 4 of human ATP7B | solution nmr | A | — | — |
| 7XUO | Structure of ATP7B C983S/C985S/D1027A mutant with cisplatin in presence of ATOX1 | electron microscopy | A | PT | 12 (best 0.82) |
| P35670 | AlphaFold monomer V2.0 prediction for copper-transporting ATPase 2 (P35670) | predicted | A | — | — |
Ligands
- PT · Platinum (II) ion · in 1 record
Experiment against prediction
- 7XUO chain A against the predicted model P35670: TM-score 0.86, RMSD 3.96 Å
- 2LQB chain A against the predicted model P35670: TM-score 0.78, RMSD 1.69 Å
- 2LQB chain A against the predicted model P35670: TM-score 0.78, RMSD 1.69 Å
- 2N7Y chain A against the predicted model P35670: TM-score 0.72, RMSD 2.20 Å
- 2N7Y chain A against the predicted model P35670: TM-score 0.72, RMSD 2.20 Å
- 2EW9 chain A against the predicted model P35670: TM-score 0.60, RMSD 4.23 Å
- 2EW9 chain A against the predicted model P35670: TM-score 0.60, RMSD 4.23 Å
- 2KOY chain A against the predicted model P35670: TM-score 0.57, RMSD 4.23 Å
- 2KOY chain A against the predicted model P35670: TM-score 0.57, RMSD 4.23 Å
- 2ARF chain A against the predicted model P35670: TM-score 0.54, RMSD 4.21 Å
Elsewhere
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