Research workbench
Haddock structure of the talin F3 domain in complex with talin 1655- 1822
Analyse Haddock structure of the talin F3 domain in complex with talin 1655- 1822 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2KGX
- Type
- protein
- Length
- 265 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Talin-1; MKIAA1027 protein
- UniProt
- P26039, Q80TM2
- Pockets
- 3 · best druggability 0.73
Structure
solution nmr · 2 distinct chains · 58% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Talin-1 | protein | 174 | 79% helix, 0% strand | P26039 |
| B | MKIAA1027 protein | protein | 91 | 18% helix, 45% strand | Q80TM2 |
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 82 | 0.73 | 0.96 | 18 | empty |
| 2 | 53 | 0.71 | 0.97 | 17 | empty |
| 3 | 220 | 0.56 | 0.79 | 30 | empty |
Interfaces
1 interface between chains.
- A–B · 1017 Ų buried · 13 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P26039
- Every structure of UniProt Q80TM2
- Elsewhere: RCSB PDB 2KGX · PDBe 2KGX · UniProt P26039 · UniProt Q80TM2
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