Research workbench
Solution structure and dynamics of the small GTPase ralb in its active conformation: significance for effector protein binding
Analyse Solution structure and dynamics of the small GTPase ralb in its active… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2KE5
- Type
- protein
- Length
- 174 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RAS-related protein ral-B
- UniProt
- P11234
- Ligands
- GNP, MG
- Pockets
- 1 · best druggability 0.48
Structure
solution nmr · 1 distinct chain · 34% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RAS-related protein ral-B | protein | 174 | 34% helix, 22% strand | P11234 |
Ligands and binding sites
- GNP · Phosphoaminophosphonic acid-guanylate ester · ligand · chains A
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 168 | 0.48 | 0.77 | 32 | GNP, MG |
Compared structures
- 2KE5 · Solution structure and dynamics of the small GTPase Ralb in its active conformation… · the same entry in another collection · chain A against A, TM-score 1.00
- P11234 · AlphaFold monomer V2.0 prediction for RAS-related protein ral-B (P11234) · a predicted model of the same protein · chain A against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P11234
- Elsewhere: RCSB PDB 2KE5 · PDBe 2KE5 · UniProt P11234
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