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Solution structure and thermodynamics of 2',5' RNA intercalation

Analyse Solution structure and thermodynamics of 2',5' RNA intercalation in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2KD4
Type
RNA
Length
16 nucleotides
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
5'-R(*GP*CP*CP*GP*CP*GP*GP*C)-2'
Ligands
PRL

Structure

solution nmr · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B5'-R(*GP*CP*CP*GP*CP*GP*GP*C)-2'rna8——

Ligands and binding sites

  • PRL · Proflavin · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 432 Ų buried · 40 hydrogen bonds · nucleic-nucleic

Compared structures

  • 2KD4 · Solution structure and thermodynamics of 2',5' RNA intercalation · the same entry in another collection · chain A against A, TM-score 1.00

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