Research workbench
Structure of P. aeruginosa acetyltransferase PA4866
Analyse Structure of P. aeruginosa acetyltransferase PA4866 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2J8M
- Type
- protein
- Length
- 341 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Acetyltransferase PA4866 from P. aeruginosa
- UniProt
- Q9HUU7
- Ligands
- AZI, SO4
- Pockets
- 1 · best druggability 0.80
Structure
x-ray diffraction · 2 distinct chains · 35% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Acetyltransferase PA4866 from P. aeruginosa | protein | 171 | 34% helix, 33% strand | Q9HUU7 |
| B | Acetyltransferase PA4866 from P. aeruginosa | protein | 170 | 35% helix, 33% strand | Q9HUU7 |
Ligands and binding sites
- AZI · Azide ion · ion · 8 copies · chains A, B
- SO4 · Sulfate ion · ion · chains B
- GOL · Glycerol · additive · 6 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1107 | 0.80 | 0.82 | 108 | AZI, GOL, SO4 |
Interfaces
1 interface between chains.
- A–B · 1718 Ų buried · 33 hydrogen bonds · protein-protein
Compared structures
- 2J8M · Structure of P. aeruginosa acetyltransferase PA4866 · the same entry in another collection · chain A against A, TM-score 1.00
- Q9HUU7 · AlphaFold monomer V2.0 prediction for L-methionine SULFOXIMINE/L-methionine sulfone… · a predicted model of the same protein · chain B against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HUU7
- Elsewhere: RCSB PDB 2J8M · PDBe 2J8M · UniProt Q9HUU7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.