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Structure of the rnai polymerase from neurospora crassa

Analyse Structure of the rnai polymerase from neurospora crassa in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2J7O
Type
protein
Length
934 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
RNA dependent RNA polymerase
UniProt
Q9Y7G6
Ligands
MG
Pockets
15 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 17% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARNA dependent RNA polymeraseprotein93440% helix, 17% strandQ9Y7G6

Ligands and binding sites

  • MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

15 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
14090.660.7950empty
25100.630.7652empty
31070.610.8725empty
41480.600.8424empty
51570.570.8124empty

Compared structures

  • 2J7O · Structure of the rnai polymerase from neurospora crassa · the same entry in another collection · chain A against A, TM-score 1.00

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