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Crystal structure of moa, a lectin from the mushroom marasmius oreades in complex with the trisaccharide GAL(1,3)GAL(1,4)GLCNAC

Analyse Crystal structure of moa, a lectin from the mushroom marasmius oreades in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2IHO
Type: protein
Length: 292 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lectin
UniProt: Q8X123
Ligands: GAL, NAG
Pockets: 1 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 18% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lectin	protein	292	18% helix, 35% strand	Q8X123

Ligands and binding sites

GAL · beta-D-galactopyranose · sugar · 4 copies · chains A
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	76	0.45	0.81	23	empty

Compared structures

2IHO · Crystal structure of MOA, a lectin from the mushroom Marasmius oreades in complex with… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8X123
Elsewhere: RCSB PDB 2IHO · PDBe 2IHO · UniProt Q8X123

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