Research workbench
Sumo protease ULP1 with the catalytic cysteine oxidized to a sulfonic acid
Analyse Sumo protease ULP1 with the catalytic cysteine oxidized to a sulfonic acid in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2HL9
- Type
- protein
- Length
- 218 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ubiquitin-like-specific protease 1
- EC
- 3.4.22.-
- UniProt
- Q02724
- Pockets
- 1 · best druggability 0.39
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ubiquitin-like-specific protease 1 (EC 3.4.22.-) | protein | 218 | 45% helix, 16% strand | Q02724 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 78 | 0.39 | 0.78 | 19 | empty |
Modifications
Observed in the structure: 1 modified (oxidation).
Compared structures
- 2HL9 · SUMO protease Ulp1 with the catalytic cysteine oxidized to a sulfonic acid · the same entry in another collection · chain A against A, TM-score 1.00
- Q02724 · AlphaFold monomer V2.0 prediction for ubiquitin-like-specific protease 1 (Q02724) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q02724
- Elsewhere: RCSB PDB 2HL9 · PDBe 2HL9 · UniProt Q02724
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