UniProt Q02724
Ubiquitin-like-specific protease 1 (Q02724)
Ubiquitin-like-specific protease 1 (UniProt Q02724), EC 3.4.22.68: 14 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q02724
- Protein
- Ubiquitin-like-specific protease 1
- EC
- 3.4.22.68
- Experimental structures
- 14
- Predicted models
- 1
- Pockets
- 9 · 2 records with a druggable one
Structures
15 records of Q02724 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1EUV | X-ray structure of the C-terminal ULP1 protease domain in complex with SMT3, the yeast ortholog of… | x-ray diffraction | A | — | — |
| 1EUV | X-ray structure of the C-terminal ULP1 protease domain in complex with SMT3, the yeast ortholog of… | x-ray diffraction | A | — | — |
| 2HKP | SUMO protease Ulp1 with the catalytic cysteine oxidized to a sulfenic acid | x-ray diffraction | A | — | — |
| 2HKP | Sumo protease ULP1 with the catalytic cysteine oxidized to a sulfenic acid | x-ray diffraction | A | — | — |
| 2HL8 | SUMO protease Ulp1 with the catalytic cysteine oxidized to a sulfinic acid | x-ray diffraction | A | — | — |
| 2HL8 | Sumo protease ULP1 with the catalytic cysteine oxidized to a sulfinic acid | x-ray diffraction | A | — | — |
| 2HL9 | SUMO protease Ulp1 with the catalytic cysteine oxidized to a sulfonic acid | x-ray diffraction | A | — | — |
| 2HL9 | Sumo protease ULP1 with the catalytic cysteine oxidized to a sulfonic acid | x-ray diffraction | A | — | — |
| 5H2V | Crystal structure of the karyopherin Kap121p bound to the SUMO protease Ulp1p | x-ray diffraction | B | — | 1 (best 0.61) |
| 5H2V | Crystal structure of the karyopherin KAP121P bound to the sumo protease ULP1P | x-ray diffraction | B | — | — |
| 5H2W | Crystal structure of the karyopherin Kap60p bound to the SUMO protease Ulp1p (150-340) | x-ray diffraction | B, D | — | 4 (best 0.55) |
| 5H2W | Crystal structure of the karyopherin KAP60P bound to the sumo protease ULP1P (150-340) | x-ray diffraction | B, D | — | — |
| 5H2X | Crystal structure of the karyopherin Kap60p bound to the SUMO protease Ulp1p (150-172) | x-ray diffraction | B | — | — |
| 5H2X | Crystal structure of the karyopherin KAP60P bound to the sumo protease ULP1P (150-172) | x-ray diffraction | B | — | — |
| Q02724 | AlphaFold monomer V2.0 prediction for ubiquitin-like-specific protease 1 (Q02724) | predicted | A | — | 4 (best 0.42) |
Experiment against prediction
- 2HL8 chain A against the predicted model Q02724: TM-score 0.99, RMSD 0.62 Å
- 2HL8 chain A against the predicted model Q02724: TM-score 0.99, RMSD 0.62 Å
- 2HKP chain A against the predicted model Q02724: TM-score 0.99, RMSD 0.63 Å
- 2HKP chain A against the predicted model Q02724: TM-score 0.99, RMSD 0.63 Å
- 2HL9 chain A against the predicted model Q02724: TM-score 0.99, RMSD 0.63 Å
- 2HL9 chain A against the predicted model Q02724: TM-score 0.99, RMSD 0.63 Å
- 1EUV chain A against the predicted model Q02724: TM-score 0.99, RMSD 0.64 Å
- 1EUV chain A against the predicted model Q02724: TM-score 0.99, RMSD 0.64 Å
- 5H2V chain B against the predicted model Q02724: TM-score 0.64, RMSD 0.42 Å
- 5H2V chain B against the predicted model Q02724: TM-score 0.64, RMSD 0.42 Å
Elsewhere
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