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NMR solution structure of the 5S rRNA E-LOOP/L25 complex

Analyse NMR solution structure of the 5S rRNA E-LOOP/L25 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
1D6K
Type
protein + RNA
Length
131 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
5S rRNA E-loop (5SE); Ribosomal protein L25
UniProt
P68919
Pockets
1 · best druggability 0.37

Structure

solution nmr · 2 distinct chains · 22% helix, 44% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
B5S rRNA E-loop (5SE)rna37——
ARibosomal protein L25protein9422% helix, 44% strandP68919

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11060.370.7517empty

Interfaces

1 interface between chains.

  • B–A · 905 Ų buried · 31 hydrogen bonds · protein-nucleic

Compared structures

  • 1D6K · NMR solution structure of the 5S rRNA E-LOOP/L25 complex · the same entry in another collection · chain B against B, TM-score 1.00

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