Research workbench

The cystal structure of the PDZ domain of human PICK1

Analyse The cystal structure of the PDZ domain of human PICK1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2GZV
Type: protein
Length: 91 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Prkca-binding protein
UniProt: Q9NRD5
Pockets: 1 · best druggability 0.34

Structure

x-ray diffraction · 1 distinct chain · 16% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Prkca-binding protein	protein	91	16% helix, 34% strand	Q9NRD5

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.34	0.78	12	empty

Compared structures

2GZV · The cystal structure of the PDZ domain of human PICK1 · the same entry in another collection · chain A against A, TM-score 1.00
Q9NRD5 · AlphaFold monomer V2.0 prediction for prkca-binding protein (Q9NRD5) · a predicted model of the same protein · chain A against A, TM-score 0.90

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9NRD5
Elsewhere: RCSB PDB 2GZV · PDBe 2GZV · UniProt Q9NRD5

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.