UniProt Q9NRD5
PRKCA-binding protein (Q9NRD5)
PRKCA-binding protein (UniProt Q9NRD5): 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NRD5
- Protein
- PRKCA-binding protein
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 8 · 0 records with a druggable one
Structures
9 records of Q9NRD5 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2GZV | The cystal structure of the PDZ domain of human PICK1 | x-ray diffraction | A | — | — |
| 2GZV | The cystal structure of the PDZ domain of human PICK1 | x-ray diffraction | A | — | — |
| 6AR4 | Crystal structure of PICK1 in complex with the small molecule inhibitor 1o | x-ray diffraction | A, B | BQA | 3 (best 0.39) |
| 6AR4 | Crystal structure of PICK1 in complex with the small molecule inhibitor 1O | x-ray diffraction | A, B | BQA | — |
| 6BJN | PICK1 PDZ domain in complex with the class I PDZ binding motif QSAV | x-ray diffraction | A, B | — | — |
| 6BJN | PICK1 PDZ domain in complex with the class I PDZ binding motif qsav | x-ray diffraction | A, B | — | — |
| 6BJO | PICK1 PDZ domain in complex with the small molecule inhibitor BIO124. | x-ray diffraction | A, B | DUY | — |
| 6BJO | PICK1 PDZ domain in complex with the small molecule inhibitor BIO124. | x-ray diffraction | A, B | DUY | — |
| Q9NRD5 | AlphaFold monomer V2.0 prediction for prkca-binding protein (Q9NRD5) | predicted | A | — | 5 (best 0.36) |
Ligands
Experiment against prediction
- 6BJO chain B against the predicted model Q9NRD5: TM-score 0.98, RMSD 0.55 Å
- 6BJO chain B against the predicted model Q9NRD5: TM-score 0.98, RMSD 0.55 Å
- 6BJO chain A against the predicted model Q9NRD5: TM-score 0.97, RMSD 0.63 Å
- 6BJO chain A against the predicted model Q9NRD5: TM-score 0.97, RMSD 0.63 Å
- 6AR4 chain A against the predicted model Q9NRD5: TM-score 0.97, RMSD 0.63 Å
- 6AR4 chain A against the predicted model Q9NRD5: TM-score 0.97, RMSD 0.63 Å
- 6AR4 chain B against the predicted model Q9NRD5: TM-score 0.97, RMSD 0.65 Å
- 6AR4 chain B against the predicted model Q9NRD5: TM-score 0.97, RMSD 0.65 Å
- 6BJN chain A against the predicted model Q9NRD5: TM-score 0.96, RMSD 0.89 Å
- 6BJN chain A against the predicted model Q9NRD5: TM-score 0.96, RMSD 0.89 Å
Elsewhere
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