Research workbench
Diabetes mellitus due to a frustrated schellman motif in hnf-1A
Analyse Diabetes mellitus due to a frustrated schellman motif in hnf-1A in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2GYP
- Type
- protein
- Length
- 66 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hepatocyte nuclear factor 1-alpha
- UniProt
- P20823
Structure
x-ray diffraction · 1 distinct chain · 73% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Hepatocyte nuclear factor 1-alpha | protein | 33 | 73% helix, 0% strand | P20823 |
Interfaces
1 interface between chains.
- A–B · 144 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 2 d-amino, 2 modified (D-amino acid, nonstandard).
Compared structures
- 2GYP · Diabetes mellitus due to a frustrated Schellman motif in HNF-1a · the same entry in another collection · chain A against A, TM-score 1.00
- P20823 · AlphaFold monomer V2.0 prediction for hepatocyte nuclear factor 1-alpha (P20823) · a predicted model of the same protein · chain A against A, TM-score 0.53
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P20823
- Elsewhere: RCSB PDB 2GYP · PDBe 2GYP · UniProt P20823
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.