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NMR structure of the human tRNA endonuclease SEN15 subunit

Analyse NMR structure of the human tRNA endonuclease SEN15 subunit in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2GW6
Type
protein
Length
246 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
TRNA-splicing endonuclease subunit SEN15
UniProt
Q8WW01

Structure

solution nmr · 1 distinct chain · 32% helix, 30% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, BTRNA-splicing endonuclease subunit SEN15protein12332% helix, 30% strandQ8WW01

Interfaces

1 interface between chains.

  • A–B · 770 Ų buried · 16 hydrogen bonds · protein-protein

Compared structures

  • 2GW6 · NMR structure of the human tRNA endonuclease SEN15 subunit · the same entry in another collection · chain A against A, TM-score 1.00
  • Q8WW01 · AlphaFold monomer V2.0 prediction for tRNA-splicing endonuclease subunit SEN15 (Q8WW01) · a predicted model of the same protein · chain A against A, TM-score 0.83

Analyse

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