Research workbench
The human EPHA3 receptor tyrosine kinase and juxtamembrane region
Analyse The human EPHA3 receptor tyrosine kinase and juxtamembrane region in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2GSF
- Type
- protein
- Length
- 281 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ephrin type-a receptor 3
- EC
- 2.7.10.1
- UniProt
- P29320
- Pockets
- 1 · best druggability 0.59
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ephrin type-a receptor 3 (EC 2.7.10.1) | protein | 281 | 41% helix, 19% strand | P29320 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 337 | 0.59 | 0.77 | 38 | empty |
Compared structures
- 2GSF · The Human Epha3 Receptor Tyrosine Kinase and Juxtamembrane Region · the same entry in another collection · chain A against A, TM-score 1.00
- P29320 · AlphaFold monomer V2.0 prediction for ephrin type-a receptor 3 (P29320) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P29320
- Elsewhere: RCSB PDB 2GSF · PDBe 2GSF · UniProt P29320
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