UniProt P29320
P29320
P29320 (UniProt P29320): 17 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P29320
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 2
Structures
18 records of P29320 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2GSF | The Human Epha3 Receptor Tyrosine Kinase and Juxtamembrane Region | x-ray diffraction | A | — | — |
| 2GSF | The human EPHA3 receptor tyrosine kinase and juxtamembrane region | x-ray diffraction | A | — | — |
| 3FXX | Human EphA3 Kinase and Juxtamembrane Region Bound to Substrate KQWDNYE[pTyr]IW | x-ray diffraction | A | — | — |
| 3FXX | Human EPHA3 kinase and juxtamembrane region bound to substrate KQWDNYE[PTYR]IW | x-ray diffraction | A | — | — |
| 3FY2 | Human EphA3 Kinase and Juxtamembrane Region Bound to Substrate KQWDNYEFIW | x-ray diffraction | A | — | — |
| 3FY2 | Human EPHA3 kinase and juxtamembrane region bound to substrate kqwdnyefiw | x-ray diffraction | A | — | — |
| 4L0P | Structure of the human EphA3 receptor ligand binding domain complexed with ephrin-A5 | x-ray diffraction | A | — | — |
| 4L0P | Structure of the human EPHA3 receptor ligand binding domain complexed with ephrin-A5 | x-ray diffraction | A | — | — |
| 4P5Q | Human EphA3 Kinase domain in complex with quinoxaline derivatives | x-ray diffraction | A | — | — |
| 4P5Q | Human EPHA3 kinase domain in complex with quinoxaline derivatives | x-ray diffraction | A | — | — |
| 4P5Z | Human EphA3 Kinase domain in complex with quinoxaline derivatives | x-ray diffraction | A | — | — |
| 4P5Z | Human EPHA3 kinase domain in complex with quinoxaline derivatives | x-ray diffraction | A | — | — |
| 4TWN | Human EphA3 Kinase domain in complex with Birb796 | x-ray diffraction | A | — | — |
| 4TWN | Human EPHA3 kinase domain in complex with BIRB796 | x-ray diffraction | A | — | — |
| 4TWO | Human EphA3 Kinase domain in complex with compound 164 | x-ray diffraction | A | — | — |
| 4TWO | Human EPHA3 kinase domain in complex with compound 164 | x-ray diffraction | A | — | — |
| 6IN0 | Crystal structure of EPHA3 in complex with 18-crown-6 | x-ray diffraction | A | CL, O4B | — |
| P29320 | AlphaFold monomer V2.0 prediction for ephrin type-a receptor 3 (P29320) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4P5Z chain A against the predicted model P29320: TM-score 0.98, RMSD 1.09 Å
- 4P5Z chain A against the predicted model P29320: TM-score 0.98, RMSD 1.09 Å
- 4P5Q chain A against the predicted model P29320: TM-score 0.97, RMSD 1.30 Å
- 4P5Q chain A against the predicted model P29320: TM-score 0.97, RMSD 1.30 Å
- 2GSF chain A against the predicted model P29320: TM-score 0.97, RMSD 1.01 Å
- 2GSF chain A against the predicted model P29320: TM-score 0.97, RMSD 1.01 Å
- 6IN0 chain A against the predicted model P29320: TM-score 0.97, RMSD 1.38 Å
- 3FY2 chain A against the predicted model P29320: TM-score 0.96, RMSD 1.31 Å
- 3FY2 chain A against the predicted model P29320: TM-score 0.96, RMSD 1.31 Å
- 4TWO chain A against the predicted model P29320: TM-score 0.96, RMSD 1.28 Å
Elsewhere
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