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1.5 a structure of bromodomain from human BRG1 protein, a central ATPase of SWI/SNF remodeling complex

Analyse 1.5 a structure of bromodomain from human BRG1 protein, a central ATPase of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2GRC
Type: protein
Length: 121 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Probable global transcription activator SNF2L4
EC: 3.6.1.-
UniProt: P51532
Pockets: 1 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 64% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Probable global transcription activator SNF2L4 (EC 3.6.1.-)	protein	121	64% helix, 2% strand	P51532

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	66	0.45	0.82	16	empty

Compared structures

2GRC · 1.5 A structure of bromodomain from human BRG1 protein, a central ATPase of SWI/SNF… · the same entry in another collection · chain A against A, TM-score 1.00
P51532 · AlphaFold monomer V2.0 prediction for transcription activator BRG1 (P51532) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P51532
Elsewhere: RCSB PDB 2GRC · PDBe 2GRC · UniProt P51532

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