Research workbench
Crystal structure of a DNA polymerase III, gamma subunit-related protein (TM0771) from thermotoga maritima MSB8 at 2.00 a resolution
Analyse Crystal structure of a DNA polymerase III, gamma subunit-related protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2GNO
- Type
- protein
- Length
- 296 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA polymerase III, gamma subunit-related protein
- UniProt
- Q9WZM9
- Ligands
- ETX, UNL, NA
- Pockets
- 3 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 62% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA polymerase III, gamma subunit-related protein | protein | 296 | 62% helix, 9% strand | Q9WZM9 |
Ligands and binding sites
- ETX · 2-ethoxyethanol · ligand · 2 copies · chains A
- UNL · Unknown ligand · ligand · chains A
- NA · Sodium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 439 | 0.60 | 0.75 | 35 | UNL |
| 2 | 73 | 0.37 | 0.77 | 13 | empty |
| 3 | 66 | 0.29 | 0.73 | 14 | NA |
Modifications
Observed in the structure: 3 modified (engineered).
Compared structures
- 2GNO · Crystal structure of a dna polymerase iii, gamma subunit-related protein (tm0771) from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9WZM9
- Elsewhere: RCSB PDB 2GNO · PDBe 2GNO · UniProt Q9WZM9
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