Research workbench
CP4 epsp synthase ALA100GLY liganded with S3P and glyphosate
Analyse CP4 epsp synthase ALA100GLY liganded with S3P and glyphosate in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2GGD
- Type
- protein
- Length
- 445 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3-phosphoshikimate 1-carboxyvinyltransferase
- EC
- 2.5.1.19
- UniProt
- Q9R4E4
- Ligands
- S3P, GPJ
- Pockets
- 3 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) | protein | 445 | 33% helix, 28% strand | Q9R4E4 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 150 | 0.72 | 0.91 | 35 | S3P, GPJ |
| 2 | 86 | 0.45 | 0.80 | 16 | empty |
| 3 | 79 | 0.29 | 0.73 | 20 | empty |
Compared structures
- 2GGD · CP4 EPSP synthase Ala100Gly liganded with S3P and Glyphosate · the same entry in another collection · chain A against A, TM-score 1.00
- Q9R4E4 · AlphaFold monomer V2.0 prediction for 3-phosphoshikimate 1-carboxyvinyltransferase… · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9R4E4
- Elsewhere: RCSB PDB 2GGD · PDBe 2GGD · UniProt Q9R4E4
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