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NMR structure of an N-terminal fragment of the eukaryotic initiation factor 5 (EIF5)

Analyse NMR structure of an N-terminal fragment of the eukaryotic initiation factor 5… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2G2K
Type: protein
Length: 156 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Eukaryotic translation initiation factor 5
UniProt: P55010
Pockets: 1 · best druggability 0.57

Structure

solution nmr · 1 distinct chain · 24% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Eukaryotic translation initiation factor 5	protein	156	24% helix, 16% strand	P55010

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	257	0.57	0.77	30	empty

Compared structures

2G2K · NMR structure of an N-terminal fragment of the eukaryotic initiation factor 5 (eIF5) · the same entry in another collection · chain A against A, TM-score 1.00
P55010 · AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 5 (P55010) · a predicted model of the same protein · chain A against A, TM-score 0.47

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P55010
Elsewhere: RCSB PDB 2G2K · PDBe 2G2K · UniProt P55010

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