UniProt P55010
Eukaryotic translation initiation factor 5 (P55010)
Eukaryotic translation initiation factor 5 (UniProt P55010): 7 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P55010
- Protein
- Eukaryotic translation initiation factor 5
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
8 records of P55010 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2E9H | Solution structure of the eIF-5_eIF-2B domain from human Eukaryotic translation initiation factor 5 | solution nmr | A | — | — |
| 2E9H | Solution structure of the eif-5_EIF-2B domain from human eukaryotic translation initiation factor 5 | solution nmr | A | — | — |
| 2G2K | NMR structure of an N-terminal fragment of the eukaryotic initiation factor 5 (eIF5) | solution nmr | A | — | — |
| 2G2K | NMR structure of an N-terminal fragment of the eukaryotic initiation factor 5 (EIF5) | solution nmr | A | — | — |
| 2IU1 | Crystal structure of eIF5 C-terminal domain | x-ray diffraction | A | — | — |
| 2IU1 | Crystal structure of EIF5 C-terminal domain | x-ray diffraction | A | — | — |
| 8OZ0 | Structure of a human 48S translation initiation complex with eIF4F and eIF4A | electron microscopy | H | — | 2 (best 0.89) |
| P55010 | AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 5 (P55010) | predicted | A | — | — |
Experiment against prediction
- 8OZ0 chain H against the predicted model P55010: TM-score 0.94, RMSD 1.15 Å
- 2IU1 chain A against the predicted model P55010: TM-score 0.92, RMSD 2.10 Å
- 2IU1 chain A against the predicted model P55010: TM-score 0.92, RMSD 2.10 Å
- 2E9H chain A against the predicted model P55010: TM-score 0.87, RMSD 1.62 Å
- 2E9H chain A against the predicted model P55010: TM-score 0.87, RMSD 1.62 Å
- 2G2K chain A against the predicted model P55010: TM-score 0.47, RMSD 4.55 Å
- 2G2K chain A against the predicted model P55010: TM-score 0.47, RMSD 4.55 Å
Elsewhere
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