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The crystal structure of the N-terminal domain of HAUSP/USP7 complexed with MDM2 peptide 147-150

Analyse The crystal structure of the N-terminal domain of HAUSP/USP7 complexed with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2FOP
Type
protein
Length
143 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Ubiquitin carboxyl-terminal hydrolase 7; MDM2 peptide
EC
3.1.2.15
UniProt
Q93009

Structure

x-ray diffraction · 2 distinct chains · 7% helix, 52% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AUbiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15)protein1377% helix, 53% strandQ93009
BMDM2 peptideprotein60% helix, 17% strand—

Interfaces

1 interface between chains.

  • A–B · 383 Ų buried · 7 hydrogen bonds · protein-protein

Compared structures

  • 2FOP · The Crystal Structure of the N-terminal domain of HAUSP/USP7 complexed with mdm2 peptide… · the same entry in another collection · chain A against A, TM-score 1.00

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