Research workbench
Complex of enzyme iiamtl and phosphorylated enzyme iibmtl from escherichia COLI NMR, restrained regularized mean structure
Analyse Complex of enzyme iiamtl and phosphorylated enzyme iibmtl from escherichia COLI… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2FEW
- Type
- protein
- Length
- 241 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pts system mannitol-specific eiicba component; Mannitol-specific pts system enzyme iiabc…
- EC
- 2.7.1.69
- UniProt
- P00550
- Pockets
- 1 · best druggability 0.43
Structure
solution nmr · 2 distinct chains · 44% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pts system mannitol-specific eiicba component (EC 2.7.1.69) | protein | 144 | 46% helix, 19% strand | P00550 |
| B | Mannitol-specific pts system enzyme iiabc components (EC 2.7.1.69) | protein | 97 | 42% helix, 23% strand | — |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 92 | 0.43 | 0.79 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 843 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
- 2FEW · Complex of enzyme IIAMTL and phosphorylated enzyme IIBMTL from Escherichia coli NMR… · the same entry in another collection · chain A against A, TM-score 1.00
- P00550 · AlphaFold monomer V2.0 prediction for pts system mannitol-specific eiicba component… · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00550
- Elsewhere: RCSB PDB 2FEW · PDBe 2FEW · UniProt P00550
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.