Research workbench
Crystal structure of enterococcus faecalis putative nicotinate phosphoribosyltransferase, new york structural genomics consortium
Analyse Crystal structure of enterococcus faecalis putative nicotinate… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2F7F
- Type
- protein
- Length
- 482 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nicotinate phosphoribosyltransferase, putative
- EC
- 2.4.2.11
- UniProt
- Q830Y8
- Ligands
- NIO, DPO, SO4
- Pockets
- 5 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nicotinate phosphoribosyltransferase, putative (EC 2.4.2.11) | protein | 482 | 41% helix, 21% strand | Q830Y8 |
Ligands and binding sites
- NIO · Nicotinic acid · ligand · 2 copies · chains A
- DPO · Diphosphate · ligand · chains A
- SO4 · Sulfate ion · ion · 8 copies · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 306 | 0.65 | 0.81 | 45 | NIO, GOL |
| 2 | 106 | 0.48 | 0.80 | 20 | empty |
| 3 | 100 | 0.48 | 0.81 | 16 | empty |
| 4 | 139 | 0.44 | 0.76 | 21 | empty |
| 5 | 107 | 0.41 | 0.77 | 22 | SO4, NIO |
Compared structures
- 2F7F · Crystal structure of Enterococcus faecalis putative nicotinate phosphoribosyltransferase… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q830Y8
- Elsewhere: RCSB PDB 2F7F · PDBe 2F7F · UniProt Q830Y8
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