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Myosin V cargo binding domain

Analyse Myosin V cargo binding domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2F6H
Type: protein
Length: 390 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Myosin-2
UniProt: P19524
Pockets: 2 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 70% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Myosin-2	protein	390	70% helix, 0% strand	P19524

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	299	0.54	0.75	36	empty
2	62	0.39	0.80	15	empty

Compared structures

2F6H · Myosin V cargo binding domain · the same entry in another collection · chain X against X, TM-score 1.00
P19524 · AlphaFold monomer V2.0 prediction for myosin-2 (P19524) · a predicted model of the same protein · chain X against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P19524
Elsewhere: RCSB PDB 2F6H · PDBe 2F6H · UniProt P19524

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