UniProt P19524
Myosin-2 (P19524)
Myosin-2 (UniProt P19524): 18 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P19524
- Protein
- Myosin-2
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 17 · 4 records with a druggable one
Structures
19 records of P19524 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1M45 | Crystal structure of MLC1P bound to IQ2 of MYO2P, a class V myosin | x-ray diffraction | B | — | — |
| 1M45 | Crystal structure of MLC1P bound to IQ2 of MYO2P, a class V myosin | x-ray diffraction | B | — | — |
| 1M46 | Crystal structure of MLC1P bound to IQ4 of MYO2P, a class V myosin | x-ray diffraction | B | — | — |
| 1M46 | Crystal structure of MLC1P bound to IQ4 of MYO2P, a class V myosin | x-ray diffraction | B | — | — |
| 1N2D | Ternary complex of MLC1P bound to IQ2 and IQ3 of Myo2p, a class V myosin | x-ray diffraction | C | — | — |
| 1N2D | Ternary complex of MLC1P bound to IQ2 and IQ3 of MYO2P, a class V myosin | x-ray diffraction | C | — | — |
| 2F6H | Myosin V cargo binding domain | x-ray diffraction | X | — | — |
| 2F6H | Myosin V cargo binding domain | x-ray diffraction | X | — | — |
| 6EYW | Structure of Yeast Myosin 5 Cargo Binding Domain in Trigonal Space Group | x-ray diffraction | X | — | 1 (best 0.53) |
| 6EYW | Structure of yeast myosin 5 cargo binding domain in trigonal space group | x-ray diffraction | X | — | — |
| 6IXO | Apo structure of Myo2-GTD | x-ray diffraction | A | SO4, CL | 1 (best 0.53) |
| 6IXO | Apo structure of MYO2-gtd | x-ray diffraction | A | SO4, CL | — |
| 6IXP | Structure of Myo2-GTD in complex with Mmr1 | x-ray diffraction | A, D | — | 8 (best 0.78) |
| 6IXP | Structure of MYO2-gtd in complex with MMR1 | x-ray diffraction | A, D | — | — |
| 6IXQ | Structure of Myo2-GTD in complex with Smy1 | x-ray diffraction | A | — | — |
| 6IXQ | Structure of MYO2-gtd in complex with SMY1 | x-ray diffraction | A | — | — |
| 6IXR | Structure of Myo2-GTD in complex with Inp2 | x-ray diffraction | A | SO4 | — |
| 6IXR | Structure of MYO2-gtd in complex with INP2 | x-ray diffraction | A | SO4 | — |
| P19524 | AlphaFold monomer V2.0 prediction for myosin-2 (P19524) | predicted | A | — | 7 (best 0.84) |
Ligands
Experiment against prediction
- 6IXO chain A against the predicted model P19524: TM-score 0.99, RMSD 0.77 Å
- 6IXO chain A against the predicted model P19524: TM-score 0.99, RMSD 0.77 Å
- 2F6H chain X against the predicted model P19524: TM-score 0.99, RMSD 0.85 Å
- 2F6H chain X against the predicted model P19524: TM-score 0.99, RMSD 0.85 Å
- 6IXP chain D against the predicted model P19524: TM-score 0.99, RMSD 0.78 Å
- 6IXP chain D against the predicted model P19524: TM-score 0.99, RMSD 0.78 Å
- 6IXP chain A against the predicted model P19524: TM-score 0.99, RMSD 0.82 Å
- 6IXP chain A against the predicted model P19524: TM-score 0.99, RMSD 0.82 Å
- 6IXR chain A against the predicted model P19524: TM-score 0.98, RMSD 1.08 Å
- 6IXR chain A against the predicted model P19524: TM-score 0.98, RMSD 1.08 Å
Elsewhere
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