Research workbench

Amino terminal domain of enzyme I from escherichia COLI, NMR, restrained regularized mean structure

Analyse Amino terminal domain of enzyme I from escherichia COLI, NMR, restrained… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2EZA
Type: protein
Length: 259 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phosphotransferase system, enzyme I
EC: 2.7.3.9
UniProt: P08839
Pockets: 3 · best druggability 0.60

Structure

solution nmr · 1 distinct chain · 54% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phosphotransferase system, enzyme I (EC 2.7.3.9)	protein	259	54% helix, 12% strand	P08839

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	358	0.60	0.77	41	empty
2	75	0.50	0.84	21	empty
3	68	0.35	0.77	18	empty

Compared structures

2EZA · Amino terminal domain of enzyme I from escherichia COLI, NMR, restrained regularized mean… · the same entry in another collection · chain A against A, TM-score 1.00
P08839 · AlphaFold monomer V2.0 prediction for phosphoenolpyruvate-protein phosphotransferase… · a predicted model of the same protein · chain A against A, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08839
Elsewhere: RCSB PDB 2EZA · PDBe 2EZA · UniProt P08839

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.