GL1X · GenesisL1 explorer

MolNFT v1 · #318133 · protein

AlphaFold monomer V2.0 prediction for phosphoenolpyruvate-protein phosphotransferase (P08839)

P08839: “AlphaFold monomer V2.0 prediction for phosphoenolpyruvate-protein phosphotransferase (P08839)”. 3 pockets (best druggability 0.75). MolNFT v1 #318133 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P08839
Type
protein
Length
575 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xd10960F956646DE8b64d3598984c91C2d5Af3D7b
Molecule
Phosphoenolpyruvate-protein phosphotransferase
UniProt
P08839
Pockets
3 · best druggability 0.75

Structure

1 distinct chain · 53% helix, 13% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APhosphoenolpyruvate-protein phosphotransferaseprotein57553% helix, 13% strandP08839

Pockets

3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
17090.750.8089empty
22160.600.8134empty
31100.530.8325empty

Compared structures

  • 2N5T · Ensemble solution structure of the phosphoenolpyruvate-enzyme I complex from the… · an experimental structure of the same protein · chain A against A, TM-score 0.75
  • 2N5T · Ensemble solution structure of the phosphoenolpyruvate-Enzyme I complex from the… · an experimental structure of the same protein · chain A against A, TM-score 0.75
  • 2HWG · Structure of phosphorylated enzyme I of the PHOSPHOENOLPYRUVATE:SUGAR phosphotransferase… · an experimental structure of the same protein · chain A against A, TM-score 0.73
  • 2HWG · Structure of phosphorylated Enzyme I of the phosphoenolpyruvate:sugar phosphotransferase… · an experimental structure of the same protein · chain A against A, TM-score 0.73
  • 2KX9 · Solution structure of the enzyme I dimer using residual dipolar couplings and small angle… · an experimental structure of the same protein · chain A against A, TM-score 0.65
  • 2KX9 · Solution Structure of the Enzyme I dimer Using Residual Dipolar Couplings and Small Angle… · an experimental structure of the same protein · chain A against A, TM-score 0.65
  • 2L5H · Solution structure of the H189Q mutant of the enzyme I dimer using residual dipolar… · an experimental structure of the same protein · chain A against A, TM-score 0.61
  • 2L5H · Solution Structure of the H189Q mutant of the Enzyme I dimer Using Residual Dipolar… · an experimental structure of the same protein · chain A against A, TM-score 0.61
  • 2XDF · Solution structure of the enzyme I dimer complexed with hpr using residual dipolar… · an experimental structure of the same protein · chain A against A, TM-score 0.55
  • 2XDF · Solution Structure of the Enzyme I Dimer Complexed with HPr Using Residual Dipolar… · an experimental structure of the same protein · chain A against A, TM-score 0.55
  • 1EZD · Amino terminal domain of enzyme I from escherichia COLI NMR, 16 structures · an experimental structure of the same protein · chain A against A, TM-score 0.43
  • 1EZD · Amino terminal domain of enzyme I from escherichia COLI NMR, 16 structures · an experimental structure of the same protein · chain A against A, TM-score 0.43

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