Research workbench
Solution structure of a biologically active human FGF-1 monomer, complexed to a hexasaccharide heparin-analogue
Analyse Solution structure of a biologically active human FGF-1 monomer, complexed to a… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2ERM
- Type
- protein
- Length
- 133 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Heparin-binding growth factor 1
- UniProt
- P05230
- Ligands
- GNS, IDR, NGY, IDS
Structure
solution nmr · 1 distinct chain · 5% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Heparin-binding growth factor 1 | protein | 133 | 5% helix, 40% strand | P05230 |
Ligands and binding sites
- GNS · 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose · ligand · 2 copies · chains A
- IDR · alpha-L-idopyranuronic acid · ligand · chains A
- NGY · 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose · ligand · chains A
- IDS · 2-O-sulfo-alpha-L-idopyranuronic acid · sugar · 2 copies · chains A
- IPA · Isopropyl alcohol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 2ERM · Solution structure of a biologically active human FGF-1 monomer, complexed to a… · the same entry in another collection · chain A against A, TM-score 1.00
- P05230 · AlphaFold monomer V2.0 prediction for fibroblast growth factor 1 (P05230) · a predicted model of the same protein · chain A against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05230
- Elsewhere: RCSB PDB 2ERM · PDBe 2ERM · UniProt P05230
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