GL1X · GenesisL1 explorer

Ligand · NGY

NGY · 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose

NGY, 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose (C8 H15 N O9 S, 301.3 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
NGY
Formula
C8 H15 N O9 S
Class
ligand
Structures
8
PDB entries
6

Binding sites

NGY in 8 structures; the first of them:

  • 5GWF · FraC with GlcNAc(6S) bound · NGY B201 · binds ARG53, GLN130, TYR133, GLU134, TYR138
  • 7P24 · Sulfated host glycan recognition by carbohydrate sulfatases of the human gut microbiota… · NGY AAA602 · binds ASP39, ASP40, LEU78, SER79, ASN100, LYS128, HIS130, GLN147 and 12 more
  • 7PRB · Crystal structure of Burkholderia pseudomallei heparanase in complex with covalent… · NGY C2 · binds GLU36, ASN69, GLY261, GLY262, HIS295, THR296, GLY297, ALA300 and 1 more
  • 7PSK · Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with… · NGY B2 · binds GLU45, ASN80, GLN293, GLY294, HIS327, GLY328, GLY329, TYR334
  • 6XKG · Crystal structure of 3-O-sulfotransferase isoform 3 in complex with 8MER oligosaccharide… · NGY E8 · binds GLU170, ARG173, ARG179, ALA355, GLU356, GLY357, HIS362, SER359 and 1 more
  • 7PR8 · Crystal structure of human heparanase in complex with covalent inhibitor GR109 · NGY D2 · binds LYS159, PHE160, GLY349, GLY350, GLN383, ALA388, TYR391, ASP62 and 1 more
  • 7PRB · Crystal structure of burkholderia pseudomallei heparanase in complex with covalent… · NGY C2 · binds GLU36, ASN69, GLY261, GLY262, HIS295, THR296, GLY297, ALA300 and 1 more
  • 7PSK · Crystal structure of beta-glucuronidase from acidobacterium capsulatum in complex with… · NGY B2 · binds GLU45, ASN80, GLN293, GLY294, HIS327, GLY328, TYR334

Residues it binds most

GLY 8, TYR 10, GLU 10, HIS 8, ASN 8, ARG 4, GLN 6, ALA 6, ASP 2, THR 4 (residue and the binding sites it lines).

Found with

  • 8I4 · (2R,3S,5R,6R)-2,3,4,5,6-pentakis(oxidanyl)cyclohexane-1-carboxylic acid
  • EDO · 1,2-ethanediol
  • CL · Chloride ion
  • A3P · Adenosine-3'-5'-diphosphate
  • NGS · 2-acetamido-2-deoxy-6-O-sulfo-beta-D-glucopyranose
  • NPO · P-nitrophenol
  • CA · Calcium ion
  • NA · Sodium ion
  • BDP · beta-D-glucopyranuronic acid
  • FUC · alpha-L-fucopyranose
  • IDS · 2-O-sulfo-alpha-L-idopyranuronic acid
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.