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Crystal structure of CEL44A, gh family 44 endoglucanase from clostridium thermocellum

Analyse Crystal structure of CEL44A, gh family 44 endoglucanase from clostridium… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2EQD
Type: protein
Length: 510 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Endoglucanase
EC: 3.2.1.4, 3.2.1.151
UniProt: P71140
Ligands: BGC, ZN, CA, CL
Pockets: 2 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 30% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Endoglucanase (EC 3.2.1.4, 3.2.1.151)	protein	510	30% helix, 28% strand	P71140

Ligands and binding sites

BGC · beta-D-glucopyranose · sugar · 8 copies · chains A
ZN · Zinc ion · metal · chains A
CA · Calcium ion · metal · chains A
CL · Chloride ion · ion · chains A
GOL · Glycerol · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	306	0.64	0.80	51	BGC, GOL
2	64	0.47	0.84	15	empty

Compared structures

2EQD · Crystal structure of Cel44A, GH family 44 endoglucanase from Clostridium thermocellum · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P71140
Elsewhere: RCSB PDB 2EQD · PDBe 2EQD · UniProt P71140

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