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Crystal structure of PDZ domain of KIAA0858 (lim), MS0793 from homo sapiens

Analyse Crystal structure of PDZ domain of KIAA0858 (lim), MS0793 from homo sapiens in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2EAQ
Type: protein
Length: 89 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lim domain only protein 7
UniProt: Q8WWI1
Ligands: NI
Pockets: 1 · best druggability 0.31

Structure

x-ray diffraction · 1 distinct chain · 20% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lim domain only protein 7	protein	89	20% helix, 43% strand	Q8WWI1

Ligands and binding sites

NI · Nickel (II) ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	59	0.31	0.75	14	empty

Compared structures

2EAQ · Crystal structure of PDZ domain of KIAA0858 (LIM), MS0793 from Homo sapiens · the same entry in another collection · chain A against A, TM-score 1.00
Q8WWI1 · AlphaFold monomer V2.0 prediction for lim domain only protein 7 (Q8WWI1) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8WWI1
Elsewhere: RCSB PDB 2EAQ · PDBe 2EAQ · UniProt Q8WWI1

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