Research workbench
Solution structure and calcium binding properties of ef-hands 3 and 4 of calsenilin
Analyse Solution structure and calcium binding properties of ef-hands 3 and 4 of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2E6W
- Type
- protein
- Length
- 96 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Calsenilin
- UniProt
- Q9Y2W7
- Ligands
- CA
- Pockets
- 1 · best druggability 0.56
Structure
solution nmr · 1 distinct chain · 52% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Calsenilin | protein | 96 | 52% helix, 4% strand | Q9Y2W7 |
Ligands and binding sites
- CA · Calcium ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 137 | 0.56 | 0.82 | 22 | empty |
Compared structures
- 2E6W · Solution structure and calcium binding properties of EF-hands 3 and 4 of calsenilin · the same entry in another collection · chain A against A, TM-score 1.00
- Q9Y2W7 · AlphaFold monomer V2.0 prediction for calsenilin (Q9Y2W7) · a predicted model of the same protein · chain A against A, TM-score 0.82
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y2W7
- Elsewhere: RCSB PDB 2E6W · PDBe 2E6W · UniProt Q9Y2W7
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