Research workbench
Crystal structure of a green fluorescent protein variant S65T/H148N at pH 9.5
Analyse Crystal structure of a green fluorescent protein variant S65T/H148N at pH 9.5 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2DUH
- Type
- protein
- Length
- 225 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Green fluorescent protein
- UniProt
- P42212
- Ligands
- C12
- Pockets
- 2 · best druggability 0.78
Structure
x-ray diffraction · 1 distinct chain · 12% helix, 52% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Green fluorescent protein | protein | 225 | 12% helix, 52% strand | P42212 |
Ligands and binding sites
- C12 · 2-(1-amino-2-hydroxypropyl)-4-(4-hydroxybenzyl)-1-(2-oxoethyl)-1H-imidazol-5-olate · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 114 | 0.78 | 0.97 | 27 | C12 |
| 2 | 58 | 0.34 | 0.77 | 11 | empty |
Modifications
Observed in the structure: 2 covalent (covalent ligand).
Compared structures
- 2DUH · crystal structure of a green fluorescent protein variant S65T/H148N at pH 9.5 · the same entry in another collection · chain A against A, TM-score 1.00
- P42212 · AlphaFold monomer V2.0 prediction for green fluorescent protein (P42212) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P42212
- Elsewhere: RCSB PDB 2DUH · PDBe 2DUH · UniProt P42212
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