GL1X · GenesisL1 explorer

Ligand · C12

C12 · 2-(1-amino-2-hydroxypropyl)-4-(4-hydroxybenzyl)-1-(2-oxoethyl)-1H-imidazol-5-olate

C12, 2-(1-amino-2-hydroxypropyl)-4-(4-hydroxybenzyl)-1-(2-oxoethyl)-1H-imidazol-5-olate (C15 H18 N3 O4 -1, 304.3 g/mol), in the MolNFT structures on GenesisL1: bound in 7 records (7 PDB entries). Every binding site with its residues within…

Component
C12
Formula
C15 H18 N3 O4 -1
Class
ligand
Structures
7
PDB entries
7

Binding sites

C12 in 7 structures; the first of them:

  • 2DUE · Crystal structure of a green fluorescent protein variant S65T/H148D at pH 10 · C12 A66 · binds LEU42, LEU44, PHE46, VAL61, THR62, THR63, PHE64, VAL68 and 14 more
  • 2DUF · Crystal structure of a green fluorescent protein variant S65T/H148D at pH 5.6 · C12 A66 · binds LEU42, LEU44, PHE46, VAL61, THR62, THR63, PHE64, VAL68 and 16 more
  • 2DUG · Crystal structure of a green fluorescent protein S65T/H148N at pH 5 · C12 A66 · binds LEU42, LEU44, PHE46, VAL61, THR62, THR63, PHE64, VAL68 and 16 more
  • 2DUH · Crystal structure of a green fluorescent protein variant S65T/H148N at pH 9.5 · C12 A66 · binds LEU42, LEU44, PHE46, VAL61, THR62, THR63, PHE64, VAL68 and 15 more
  • 2FZU · Reduced enolate chromophore intermediate for GFP variant · C12 A66 · binds LEU42, LEU44, PHE46, VAL61, THR62, THR63, LEU64, VAL68 and 14 more
  • 3OSQ · Maltose-bound maltose sensor engineered by insertion of circularly permuted green… · C12 A340 · binds HIS177, VAL179, PHE194, ILE196, THR232, SER234, LEU249, GLU251 and 15 more
  • 3OSR · Maltose-bound maltose sensor engineered by insertion of circularly permuted green… · C12 A478 · binds VAL317, PHE332, ILE334, THR370, SER372, LEU387, GLU389, LEU454 and 14 more

Residues it binds most

VAL 8, LEU 8, THR 8, PHE 8, GLN 8, ASN 8, TYR 8, ARG 8, GLU 8, SER 8 (residue and the binding sites it lines).

Found with

  • GLC · alpha-D-glucopyranose
  • MG · Magnesium ion
  • SO4 · Sulfate ion
  • EDO · 1,2-ethanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.