Research workbench

Solution structure of splicing factor motif in pre-mRNA splicing factor 18 (HPRP18)

Analyse Solution structure of splicing factor motif in pre-mRNA splicing factor 18… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2DK4
Type: protein
Length: 76 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pre-mRNA-splicing factor 18
UniProt: Q99633
Pockets: 1 · best druggability 0.55

Structure

solution nmr · 1 distinct chain · 33% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pre-mRNA-splicing factor 18	protein	76	33% helix, 0% strand	Q99633

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	188	0.55	0.80	22	empty

Compared structures

2DK4 · Solution structure of Splicing Factor Motif in Pre-mRNA splicing factor 18 (hPRP18) · the same entry in another collection · chain A against A, TM-score 1.00
Q99633 · AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor 18 (Q99633) · a predicted model of the same protein · chain A against A, TM-score 0.52

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q99633
Elsewhere: RCSB PDB 2DK4 · PDBe 2DK4 · UniProt Q99633

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.