MolNFT v1 · #311064 · protein
AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor 18 (Q99633)
Q99633: “AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor 18 (Q99633)”. 6 pockets (best druggability 0.38). MolNFT v1 #311064 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q99633
- Type
- protein
- Length
- 342 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xaa53776A41fB2e67da75A96E8a53746b6874aAB4
- Molecule
- Pre-mRNA-splicing factor 18
- UniProt
- Q99633
- Pockets
- 6 · best druggability 0.38
Structure
1 distinct chain · 60% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pre-mRNA-splicing factor 18 | protein | 342 | 60% helix, 0% strand | Q99633 |
Pockets
6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 112 | 0.38 | 0.74 | 16 | empty |
| 2 | 109 | 0.34 | 0.73 | 26 | empty |
| 3 | 73 | 0.32 | 0.75 | 17 | empty |
| 4 | 71 | 0.28 | 0.72 | 13 | empty |
| 5 | 70 | 0.27 | 0.72 | 16 | empty |
Compared structures
- 2DK4 · Solution structure of splicing factor motif in pre-mRNA splicing factor 18 (HPRP18) · an experimental structure of the same protein · chain A against A, TM-score 0.13
- 2DK4 · Solution structure of Splicing Factor Motif in Pre-mRNA splicing factor 18 (hPRP18) · an experimental structure of the same protein · chain A against A, TM-score 0.13
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99633
- Elsewhere: UniProt Q99633 · AlphaFold DB Q99633
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