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Solution structure of the 9TH filamin domain from human filamin-B

Analyse Solution structure of the 9TH filamin domain from human filamin-B in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2DI9
Type
protein
Length
131 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Filamin-B
UniProt
O75369
Pockets
1 · best druggability 0.34

Structure

solution nmr · 1 distinct chain · 5% helix, 34% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AFilamin-Bprotein1315% helix, 34% strandO75369

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1900.340.7421empty

Compared structures

  • 2DI9 · Solution structure of the 9th filamin domain from human Filamin-B · the same entry in another collection · chain A against A, TM-score 1.00
  • O75369 · AlphaFold monomer V2.0 prediction for filamin-B (O75369) · a predicted model of the same protein · chain A against A, TM-score 0.76

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