UniProt O75369
Filamin-B (O75369)
Filamin-B (UniProt O75369): 46 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75369
- Protein
- Filamin-B
- Experimental structures
- 46
- Predicted models
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
47 records of O75369 in the MolNFT archive: 46 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2DI8 | Solution structure of the 19th filamin domain from human Filamin-B | solution nmr | A | — | — |
| 2DI8 | Solution structure of the 19TH filamin domain from human filamin-B | solution nmr | A | — | — |
| 2DI9 | Solution structure of the 9th filamin domain from human Filamin-B | solution nmr | A | — | — |
| 2DI9 | Solution structure of the 9TH filamin domain from human filamin-B | solution nmr | A | — | — |
| 2DIA | Solution structure of the 10th filamin domain from human Filamin-B | solution nmr | A | — | — |
| 2DIA | Solution structure of the 10TH filamin domain from human filamin-B | solution nmr | A | — | — |
| 2DIB | Solution structure of the 11th filamin domain from human Filamin-B | solution nmr | A | — | — |
| 2DIB | Solution structure of the 11TH filamin domain from human filamin-B | solution nmr | A | — | — |
| 2DIC | Solution structure of the 12th filamin domain from human Filamin-B | solution nmr | A | — | — |
| 2DIC | Solution structure of the 12TH filamin domain from human filamin-B | solution nmr | A | — | — |
| 2DJ4 | Solution structure of the 13th filamin domain from human Filamin-B | solution nmr | A | — | — |
| 2DJ4 | Solution structure of the 13TH filamin domain from human filamin-B | solution nmr | A | — | — |
| 2DLG | Solution structure of the 20th Filamin domain from human Filamin-B | solution nmr | A | — | — |
| 2DLG | Solution structure of the 20TH filamin domain from human filamin-B | solution nmr | A | — | — |
| 2DMB | Solution structure of the 15th Filamin domain from human Filamin-B | solution nmr | A | — | — |
| 2DMB | Solution structure of the 15TH filamin domain from human filamin-B | solution nmr | A | — | — |
| 2DMC | Solution structure of the 18th Filamin domain from human Filamin-B | solution nmr | A | — | — |
| 2DMC | Solution structure of the 18TH filamin domain from human filamin-B | solution nmr | A | — | — |
| 2E9I | Solution structure of the N-terminal extended 20th Filamin domain from human Filamin-B | solution nmr | A | — | — |
| 2E9I | Solution structure of the N-terminal extended 20TH filamin domain from human filamin-B | solution nmr | A | — | — |
| 2E9J | Solution structure of the 14th filamin domain from human Filamin-B | solution nmr | A | — | — |
| 2E9J | Solution structure of the 14TH filamin domain from human filamin-B | solution nmr | A | — | — |
| 2EE6 | Solution structure of the 21th filamin domain from human Filamin-B | solution nmr | A | — | — |
| 2EE6 | Solution structure of the 21TH filamin domain from human filamin-B | solution nmr | A | — | — |
| 2EE9 | Solution structure of the 16th filamin domain from human Filamin-B | solution nmr | A | — | — |
| 2EE9 | Solution structure of the 16TH filamin domain from human filamin-B | solution nmr | A | — | — |
| 2EEA | Solution structure of the 17th filamin domain from human Filamin-B | solution nmr | A | — | — |
| 2EEA | Solution structure of the 17TH filamin domain from human filamin-B | solution nmr | A | — | — |
| 2EEB | Solution structure of the 22th filamin domain from human Filamin-B | solution nmr | A | — | — |
| 2EEB | Solution structure of the 22TH filamin domain from human filamin-B | solution nmr | A | — | — |
| 2EEC | Solution structure of the 23th filamin domain from human Filamin-B | solution nmr | A | — | — |
| 2EEC | Solution structure of the 23TH filamin domain from human filamin-B | solution nmr | A | — | — |
| 2EED | Solution structure of the 24th filamin domain from human Filamin-B | solution nmr | A | — | — |
| 2EED | Solution structure of the 24TH filamin domain from human filamin-B | solution nmr | A | — | — |
| 2WA5 | Crystal structure of human filamin B actin binding domain at 1.9 Angstroms resolution | x-ray diffraction | A | — | — |
| 2WA5 | Crystal structure of human filamin B actin binding domain at 1.9 ångströms resolution | x-ray diffraction | A | — | — |
| 2WA6 | Structure of the W148R mutant of human filamin b actin binding domain at 1.95 Angstrom resolution | x-ray diffraction | A | — | — |
| 2WA6 | Structure of the W148R mutant of human filamin B actin binding domain at 1.95 ångström resolution | x-ray diffraction | A | — | — |
| 2WA7 | Structure of the M202V mutant of human filamin b actin binding domain at 1.85 Angstrom resolution | x-ray diffraction | A | — | — |
| 2WA7 | Structure of the M202V mutant of human filamin B actin binding domain at 1.85 ångström resolution | x-ray diffraction | A | — | — |
| 3FER | Crystal structure of n-terminal actin-binding domain from human filamin b (tandem ch-domains).… | x-ray diffraction | A, B, C, D | — | — |
| 3FER | Crystal structure of N-terminal actin-binding domain from human filamin B (tandem ch-domains).… | x-ray diffraction | A, B, C, D | — | — |
| 4B7L | Crystal Structure of Human Filamin B Actin Binding Domain with 1st Filamin Repeat | x-ray diffraction | A, B | — | — |
| 4B7L | Crystal structure of human filamin B actin binding domain with 1ST filamin repeat | x-ray diffraction | A, B | — | — |
| 5DCP | Crystal structure of the human filamin B Ig-like domains 16-17 | x-ray diffraction | A, B | — | 3 (best 0.70) |
| 5DCP | Crystal structure of the human filamin B ig-like domains 16-17 | x-ray diffraction | A, B | — | — |
| O75369 | AlphaFold monomer V2.0 prediction for filamin-B (O75369) | predicted | A | — | — |
Experiment against prediction
- 3FER chain C against the predicted model O75369: TM-score 0.99, RMSD 0.72 Å
- 3FER chain C against the predicted model O75369: TM-score 0.99, RMSD 0.72 Å
- 3FER chain B against the predicted model O75369: TM-score 0.98, RMSD 0.91 Å
- 3FER chain B against the predicted model O75369: TM-score 0.98, RMSD 0.91 Å
- 3FER chain A against the predicted model O75369: TM-score 0.98, RMSD 0.93 Å
- 3FER chain A against the predicted model O75369: TM-score 0.98, RMSD 0.93 Å
- 3FER chain D against the predicted model O75369: TM-score 0.98, RMSD 0.88 Å
- 3FER chain D against the predicted model O75369: TM-score 0.98, RMSD 0.88 Å
- 2WA7 chain A against the predicted model O75369: TM-score 0.98, RMSD 0.91 Å
- 2WA7 chain A against the predicted model O75369: TM-score 0.98, RMSD 0.91 Å
Elsewhere
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