MolNFT v1 · #52752 · protein
Crystal structure of human filamin B actin binding domain at 1.9 ångströms resolution
2WA5 · Filamin-B: “Crystal structure of human filamin B actin binding domain at 1.9 ångströms resolution”. X-ray diffraction, 2 ligands (CO3, SO4), 1 pocket (best druggability 0.32). MolNFT v1 #52752 on GenesisL1: 3D structure, binding…
- PDB
- 2WA5
- Type
- protein
- Length
- 237 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Filamin-B
- UniProt
- O75369
- Ligands
- CO3, SO4
- Pockets
- 1 · best druggability 0.32
Structure
x-ray diffraction · 1 distinct chain · 58% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Filamin-B | protein | 237 | 58% helix, 0% strand | O75369 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 76 | 0.32 | 0.74 | 16 | empty |
Compared structures
- 2WA5 · Crystal structure of human filamin B actin binding domain at 1.9 Angstroms resolution · the same entry in another collection · chain A against A, TM-score 1.00
- O75369 · AlphaFold monomer V2.0 prediction for filamin-B (O75369) · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O75369
- Elsewhere: RCSB PDB 2WA5 · PDBe 2WA5 · UniProt O75369
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