Research workbench
The structure of siglec-7 in complex with ALPHA(2,3)/ALPHA(2,6) disialyl lactotetraosyl 2-(TRIMETHYLSILYL)ETHYL
Analyse The structure of siglec-7 in complex with ALPHA(2,3)/ALPHA(2,6) disialyl… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2DF3
- Type
- protein
- Length
- 114 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sialic acid-binding ig-like lectin 7
- UniProt
- Q9Y286
- Ligands
- CYS, NAG, SIA, GAL
Structure
x-ray diffraction · 1 distinct chain · 5% helix, 43% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sialic acid-binding ig-like lectin 7 | protein | 114 | 5% helix, 43% strand | Q9Y286 |
Ligands and binding sites
- CYS · Cysteine · ligand · chains A
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
- SIA · N-acetyl-alpha-neuraminic acid · sugar · 2 copies · chains A
- GAL · beta-D-galactopyranose · sugar
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Modifications
Observed in the structure: 1 covalent, 1 disulfide, 1 glycan (covalent ligand, disulfide, N-glycosylation).
Compared structures
- 2DF3 · The structure of Siglec-7 in complex with alpha(2,3)/alpha(2,6) disialyl lactotetraosyl… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9Y286 · AlphaFold monomer V2.0 prediction for sialic acid-binding ig-like lectin 7 (Q9Y286) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y286
- Elsewhere: RCSB PDB 2DF3 · PDBe 2DF3 · UniProt Q9Y286
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