Research workbench
Crystal structure of a mutant elongation factor G trapped with a GTP analogue
Analyse Crystal structure of a mutant elongation factor G trapped with a GTP analogue in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2BV3
- Type
- protein
- Length
- 632 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Elongation factor G
- UniProt
- P13551
- Ligands
- GNP, MG
- Pockets
- 9 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 26% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Elongation factor G | protein | 632 | 26% helix, 34% strand | P13551 |
Ligands and binding sites
- GNP · Phosphoaminophosphonic acid-guanylate ester · ligand · chains A
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 632 | 0.70 | 0.78 | 62 | empty |
| 2 | 465 | 0.70 | 0.81 | 69 | empty |
| 3 | 65 | 0.65 | 0.93 | 17 | empty |
| 4 | 152 | 0.54 | 0.80 | 24 | empty |
| 5 | 51 | 0.37 | 0.80 | 19 | empty |
Compared structures
- 2BV3 · Crystal structure of a mutant elongation factor G trapped with a GTP analogue · the same entry in another collection · chain A against A, TM-score 1.00
- P13551 · AlphaFold monomer V2.0 prediction for elongation factor G (P13551) · a predicted model of the same protein · chain A against A, TM-score 0.77
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P13551
- Elsewhere: RCSB PDB 2BV3 · PDBe 2BV3 · UniProt P13551
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