Research workbench
Physarum polycephalum myosin II regulatory domain
Analyse Physarum polycephalum myosin II regulatory domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2BL0
- Type
- protein
- Length
- 350 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Major plasmodial myosin heavy chain; Myosin regulatory light chain
- EC
- 3.6.1.32
- UniProt
- Q9BJD3, P08053, Q8WSQ4
- Ligands
- CA
- Pockets
- 1 · best druggability 0.49
Structure
x-ray diffraction · 3 distinct chains · 63% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Major plasmodial myosin heavy chain (EC 3.6.1.32) | protein | 63 | 89% helix, 0% strand | Q9BJD3 |
| B | Myosin regulatory light chain (EC 3.6.1.32) | protein | 145 | 57% helix, 7% strand | P08053 |
| C | Myosin regulatory light chain (EC 3.6.1.32) | protein | 142 | 58% helix, 7% strand | Q8WSQ4 |
Ligands and binding sites
- CA · Calcium ion · metal · 2 copies · chains B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 200 | 0.49 | 0.76 | 30 | empty |
Interfaces
3 interfaces between chains.
- A–C · 2058 Ų buried · 17 hydrogen bonds · protein-protein
- A–B · 1637 Ų buried · 18 hydrogen bonds · protein-protein
- B–C · 70 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9BJD3
- Every structure of UniProt P08053
- Every structure of UniProt Q8WSQ4
- Elsewhere: RCSB PDB 2BL0 · PDBe 2BL0 · UniProt Q9BJD3 · UniProt P08053 · UniProt Q8WSQ4
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