Research workbench
Nikr with bound nickel and phosphate
Analyse Nikr with bound nickel and phosphate in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2BJ9
- Type
- protein
- Length
- 271 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nickel responsive regulator
- UniProt
- O58316
- Ligands
- NI, PO4
- Pockets
- 2 · best druggability 0.70
Structure
x-ray diffraction · 2 distinct chains · 39% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nickel responsive regulator | protein | 133 | 38% helix, 36% strand | O58316 |
| B | Nickel responsive regulator | protein | 138 | 40% helix, 35% strand | O58316 |
Ligands and binding sites
- NI · Nickel (II) ion · metal · 5 copies · chains A, B
- PO4 · Phosphate ion · ion · 2 copies · chains A, B
- PG4 · Tetraethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 375 | 0.70 | 0.82 | 44 | empty |
| 2 | 101 | 0.39 | 0.76 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 3294 Ų buried · 29 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O58316
- Elsewhere: RCSB PDB 2BJ9 · PDBe 2BJ9 · UniProt O58316
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.