Research workbench
Crystal structure of apocarotenoid cleavage oxygenase from synechocystis, fe-free apoenzyme
Analyse Crystal structure of apocarotenoid cleavage oxygenase from synechocystis… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2BIX
- Type
- protein
- Length
- 958 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Apocarotenoid-cleaving oxygenase
- UniProt
- P74334
- Pockets
- 7 · best druggability 0.85
Structure
x-ray diffraction · 1 distinct chain · 8% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Apocarotenoid-cleaving oxygenase | protein | 479 | 8% helix, 41% strand | P74334 |
Ligands and binding sites
- C8E · (hydroxyethyloxy)tri(ethyloxy)octane · additive · 2 copies · chains A, B
- GOL · Glycerol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1084 | 0.85 | 0.86 | 75 | C8E |
| 2 | 1194 | 0.84 | 0.85 | 81 | C8E, GOL |
| 3 | 409 | 0.78 | 0.87 | 41 | empty |
| 4 | 445 | 0.77 | 0.86 | 37 | empty |
| 5 | 118 | 0.56 | 0.83 | 17 | empty |
Compared structures
- 2BIX · Crystal structure of apocarotenoid cleavage oxygenase from Synechocystis, Fe-free… · the same entry in another collection · chain A against A, TM-score 1.00
- P74334 · AlphaFold monomer V2.0 prediction for apocarotenoid-15,15'-oxygenase (P74334) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P74334
- Elsewhere: RCSB PDB 2BIX · PDBe 2BIX · UniProt P74334
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.